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Quantitative Biosciences and Engineering

Bachelor of Science

Delivery Options

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Fall 2027 Deadline

Priority: November 1
Regular: January 15
Late: April 1

Why Quantitative Biosciences and Engineering?

Few degrees can match quantitative biosciences and engineering in terms of applying engineering principles to drive discovery at the molecular, cellular and systems level. As you learn about how genes, cells and organisms function, you will design technologies to enhance health, energy and the environment. It’s a field where computational tools and experimental biology merge to reveal how life works and how it can be reshaped for good. Your interests could lead you into bioinformatics and computational biology, as well as fields such as gene editing and synthetic biology, tissue engineering and environmental biology, including engineering microbes for carbon capture, pollution cleanup and ecosystem restoration.

 

Program Overview

A Bachelor of Science in Quantitative Biosciences and Engineering at Mines invites you to combine skills, passion and perspectives from biology, mathematics, computer science, chemistry and engineering to solve the toughest challenges in medicine, biotechnology and emerging biological fields.

The interdisciplinary Mines Quantitative Biosciences and Engineering program recognizes that the future of all bioscience breakthroughs (products, medicines, therapies and technologies) requires next-level computing/machine learning, data science and engineering knowledge and experience. 

You will benefit from lab courses that provide hands-on experience with advanced molecular biology techniques, including PCR (polymerase chain reaction) and CRISPR-Cas9, among others. You will learn mathematical modeling, data analysis and computational biology skills and be positioned for a variety of graduate studies, research and industry roles, such as:

  • Bioinformatics
  • Computational Biology/Gene Editing
  • Biomedical Engineering
  • Quantitative Biomedicine
  • Environmental and Quantitative Biology

 

Program Focus

You will discover a flexible quantitative biosciences and engineering program that gathers faculty, graduate and undergraduate students from diverse backgrounds and life experiences. You will connect with this community around a shared interest in biosciences and in developing novel approaches to solve real-world problems.

Program Design/Options

The Bachelor of Science in Quantitative Biosciences and Engineering program at Mines emphasizes hands-on quantitative training in biology, chemistry and physics, as well as mathematics and computer science. You will complete a quantitative skills core that includes the general Mines core curriculum plus a set of additional required courses in quantitative bioscience and engineering. 

An approved stream of biology electives are then added that are designed to support you with an interest in a particular area of biology (e.g., pre-med, ecology, systems, molecular). Review all course descriptions here

You can choose from electives in pre-med, ecology systems and molecular biology.  Minor options include: biomedical engineering minor, biomechanical engineering minor and a data science minor. You can review the full 4-Year Plan for the Bachelor of Science in Quantitative Biosciences and Engineering program classes and electives by downloading the 4-Year Plan for the 2023-2024 Catalog.

 

Combined 4+1 BS/MS Program 

As a Mines undergraduate student, you have the opportunity to earn a master’s degree while completing a bachelor’s degree. This five-year pathway is designed to reduce time and cost and give you the tools and capabilities needed to solve hard problems in the world.

Learn more about combined BS/MS programs >

Program Opportunities

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Graduate/Research Opportunities

You will further develop skills through research and other independent study opportunities in partnership with several research labs across campus. Research is often collaborative, involving collaborations with local medical institutions (e.g., Children’s Hospital of Colorado, CU Anschutz Medical Campus) and national laboratories.

  • Mines Undergraduate Research Fellowship (MURF)
    Work as research assistants on faculty-led research projects and broaden and deepen your grasp of the research enterprise. See the MURF website for details.
  • First-Year Innovation and Research Scholar Training
    Pursue a First-Year Innovation and Research Scholar Training (FIRST) Fellowship and participate in original research experiences coupled with a focus on innovation. As a FIRST fellowship recipient, you receive up to a $1,000 stipend, disbursed hourly, to compensate for your time spent on research. See the FIRST website for details.
A female student conducting research at the Edgar Experimental Mine in Idaho Springs, Colorado, during the inaugural field session for the Colorado School of Mines' Quantitative Biosciences and Engineering program
Industry Opportunities

As a graduate of the Quantitative Biosciences and Engineering program at Mines, you stand out from general biology majors. You are prepared to work in research and development, applied technical laboratories and the biotech industry. Colorado’s biotechnology landscape features global industry leaders, innovative startups and specialized research labs across various sectors, including pharmaceuticals, diagnostics, genomics, agricultural biotechnology and medical devices. Major employers include Johnson & Johnson, Novartis and Thermo Fisher Scientific. Emerging biotech and life sciences firms include Atara Biotherapeutics (T-cell immunotherapy/Denver), TriSalus Life Sciences (immunotherapy/Westminster) and SomaLogic (precision medicine/Boulder). Technical and research laboratories include the Sequencing Center (advanced DNA sequencing) and Flagship Biosciences (AI-powered tissue analysis).

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Medical School

You may consider pursuing medical school after earning your bachelor’s degree from Mines, including traditional and emerging medical training programs that combine engineering or computer science with medicine. Examples include the Texas A&M EnMed (Engineering Medicine) program, the Arizona State University (ASU) School of Medicine Advanced Medical Engineering program and the Carle Illinois College of Medicine. All aim to graduate “physicianeers” who can combine medicine, hands-on device and software engineering and entrepreneurship in healthcare.

Salaries and Career Outlook

$73,500 Median starting salary for recent program graduates
#1 Mines ranks #1 for return on investment (ROI) among Colorado public universities
94% Graduates with positive career outcomes
#4 Mines ranks #4 amongst top brainiest colleges in the U.S.

Program Curriculum

View Academic Catalog

Faculty Expertise

Meet three renowned faculty experts in computational biology, systems biology and synthetic biology who provide the rigorous quantitative expertise you need to solve complex challenges in the life sciences and biotechnology sectors.

John Spear profile picture

John Spear

Professor

Ramya Kumar profile picture

Ramya Kumar

Assistant Professor

Anne Silverman profile picture

Anne Silverman

Professor

World-Class Labs, Centers and Facilities

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Functional Biomechanics Laboratory

The Functional Biomechanics Laboratory improves mobility in impaired and at-risk populations through targeted rehabilitation programs and device interventions. Led by Professor Anne Silverman, the lab investigates whole-body biomechanics with experimental and computational approaches, using motion capture, ground reaction force measurement and electromyography to quantify walking mechanics, coupled with detailed musculoskeletal models to generate movement simulations

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Diniz Behn Research Group

Professor Cecilia Diniz Behn applies multiscale mathematical modeling to investigate key research questions in metabolism, sleep and circadian rhythms. Her research group models key dynamics in whole-body metabolism including changes in glucose, glycerol, and insulin; sleep and circadian neurophysiology; and the diverse interactions among these systems.

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Krebs Research Group

Associate Professor Melissa Krebs develops biopolymer systems that allow the study of cells’ interactions with their microenvironment and that can be used for both tissue regeneration and therapeutics, with the end goal of improving patient therapies that are available in the clinic.

Frequently Asked Questions

What is quantitative biosciences and engineering?

Quantitative biosciences and engineering (QBE) is an interdisciplinary field focused on using mathematics, computation, engineering and advanced quantitative methods to analyze and solve complex biological problems. This approach enables deeper understanding, prediction and manipulation of biological systems—from molecules to ecosystems—through data-driven, cross-disciplinary techniques.​

Quantitative biosciences and engineering merges training in biology with rigorous skills in mathematics, computational science, physics, chemistry and engineering. The aim is to prepare scientists and engineers who can tackle real-world biological questions using quantitative models, big data analysis and computational tools. You will gain hands-on research experience, often in collaboration with faculty from diverse scientific backgrounds and are prepared for innovation at the intersection of these disciplines.​

What are the most interesting advances and technologies in quantitative biosciences and engineering?

Recent advances shaping QBE include high-throughput DNA sequencing, single-cell genomics, computational modeling of biological networks, systems biology, synthetic biology, machine learning applied to biological data and genome editing technologies like CRISPR. Modern QBE also leverages powerful statistical, data science and visualization tools to model complex biological systems, while advances in bioengineering are leading to new biomaterials, tissues and sustainable bioproducts.​

Career Options with a QBE Degree

Graduates with a degree in quantitative biosciences and engineering pursue diverse roles such as:

  • Bioinformatics or data scientist
  • Biostatistician
  • Biomedical or clinical engineer
  • Imaging scientist
  • Research scientist (in pharmaceuticals, agricultural biotech or environmental biosciences)
  • Quantitative biologist
  • Positions in medical, public health or clinical research
  • Many also pursue graduate or professional degrees in medicine, biomedical research or engineering.​
What industries are hiring quantitative biosciences and engineering graduates?

Industries that commonly employ QBE graduates include:

  • Biotechnology and pharmaceuticals
  • Medical device and diagnostics companies
  • Healthcare and hospital systems
  • Environmental and sustainability sectors
  • Academic and government research labs
  • Data science or analytics firms with a health/life sciences focus
  • Food and agriculture technology, as well as startups focused on bio-based products.​
What are the current research directions in quantitative biosciences and engineering?

Current research in QBE is rapidly expanding into areas such as:

  • Synthetic and systems biology—designing novel genetic circuits and reprogramming cellular systems
  • Computational modeling of diseases, complex biological systems and epidemiology
  • Environmental biosciences, including bioremediation and bioenergy
  • Development of new diagnostic and therapeutic technologies (e.g., precision medicine, wearable biosensors)
  • Machine learning for big biological data, including image and omics data analysis
  • Modeling biological networks and evolutionary processes.​

This multidisciplinary field continues to evolve rapidly and offers exciting opportunities for research, innovation and impactful careers that bridge biology, engineering and computation.

Featured Alumni

Meet Amit Sela ’24, Quantitative Biosciences and Engineering

Originally, I chose to come to Mines largely due to its reputation of being an amazing engineering school, and the fact that it was introducing a brand new bio-related program (QBE) the year that I was starting. However, Mines exceeded my expectations on every single level. I would have to say that what I enjoyed the most about being at Mines was the community. I truly felt that I was always part of a family, whether I was in my major-related classes, my research lab, or my job as a peer mentor. It's a really unique place, and I would not have chosen to go to school anywhere else.