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Quantitative Biosciences and Engineering (Non-Thesis)

Master of Science

Delivery Options

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Fall 2026 Deadline

Domestic: August 1st
International: March 1st

Why study this degree at Mines?

If you’re ready to explore what’s next in biology and health through the lens of science and engineering, the Master of Science in Quantitative Biosciences and Engineering (Non-Thesis) at Colorado School of Mines can help you pursue those goals. 

This interdisciplinary program spanning chemistry, physics, computer science, mathematics, engineering and geosciences will give you the skills to tackle challenges at the intersection of biology, health and technology. You’ll gain hands-on experience and computational expertise in areas ranging from bioinformatics, computational biology and systems biology to biomechanics, tissue engineering, biosensors and biofuels. Labs and courses integrate cutting-edge techniques, including laser imaging, CRISPR-Cas9, metabolic engineering and digital healthcare, preparing you to model, analyze and optimize complex biological systems. You will be prepared to lead and innovate in biotechnology, healthcare, environmental biology and beyond or pursue further graduate studies.

With a Master of Science in Quantitative Biosciences and Engineering (Non-Thesis), you will be well-equipped to turn complex biological challenges into actionable solutions that shape the future of biotechnology, healthcare and life sciences.

Program Detail

The Master of Science in Quantitative Biosciences and Engineering (Non-Thesis) gives students a solid foundation in biology, chemistry, mathematics, computer science and engineering to tackle real-world challenges in medicine, biotechnology and emerging biological technologies. This interdisciplinary program draws on more than 35 faculty across campus and integrates expertise from fields such as chemical and biological engineering, mechanical engineering, civil and environmental engineering, physics and applied mathematics.

You’ll build core knowledge in cell biology, biochemistry, bioinformatics, systems biology and physical biochemistry, while selecting electives that expand your skills in computational biology, tissue engineering, biosensors, digital healthcare, metabolic engineering and biomechanics. Through coursework and seminars, you’ll gain hands-on lab experience, computational modeling expertise and the ability to analyze complex biological systems.

Faculty Expertise

Meet three renowned faculty experts in computational biology, systems biology and synthetic biology who provide the rigorous quantitative expertise you need to solve complex challenges in the life sciences and biotechnology sectors.

Kevin Cash profile picture

Kevin Cash

Associate Professor

Anne Silverman profile picture

Anne Silverman

Professor

Cecilia Diniz Behn profile picture

Cecilia Diniz Behn

Professor

Application Requirements

  • Bachelor's degree

  • GRE: Not Required

  • Letters of Recommendations (2 letters). Letters are not required for current Mines students.

  • Resume or Curriculum Vitae (CV)

  • Statement of Purpose

  • Transcripts

  • International students please review the English proficiency requirements

Program Curriculum

View Academic Catalog

World Class Labs, Centers and Facilities

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Functional Biomechanics Laboratory

The Functional Biomechanics Laboratory improves mobility in impaired and at-risk populations through targeted rehabilitation programs and device interventions. Led by Professor Anne Silverman, the lab investigates whole-body biomechanics with experimental and computational approaches, using motion capture, ground reaction force measurement and electromyography to quantify walking mechanics, coupled with detailed musculoskeletal models to generate movement simulations

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Diniz Behn Research Group

Professor Cecilia Diniz Behn applies multiscale mathematical modeling to investigate key research questions in metabolism, sleep and circadian rhythms. Her research group models key dynamics in whole-body metabolism including changes in glucose, glycerol, and insulin; sleep and circadian neurophysiology; and the diverse interactions among these systems.

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Krebs Research Group

Associate Professor Melissa Krebs develops biopolymer systems that allow the study of cells’ interactions with their microenvironment and that can be used for both tissue regeneration and therapeutics, with the end goal of improving patient therapies that are available in the clinic.

Career Outlook

Median salary for recent program graduates $61,000. Learn more about Mines' comprehensive career development resources and this degree's salary potential.

Explore Mines Career Center

Employers who seek Mines graduates include

Biotechnology, Pharmaceuticals and Medical Devices

Companies such as

  • Agilent Technologies
  • Biodesix
  • Foresight Diagnostics
  • Medtronic
  • Pfizer
  • SomaLogic (now Standard BioTools)
  • Terumo Blood and Cell Technologies
  • Tolmar
  • Umoja Biopharma
Healthcare and Clinical Diagnostics

Companies such as

  • CCRM Fertility
  • Children's Hospital Colorado
  • DaVita
  • Stryker
  • University of Colorado Anschutz Medical Campus
Research, Government and National Laboratories

Companies such as

  • Los Alamos National Laboratory (LANL)
  • National Renewable Energy Laboratory (NRL)
  • National Jewish Health
  • U.S. Geological Survey (USGS)

 

Technology, Data Science and Engineering

Companies such as

  • Lockheed Martin (Human Systems/Bio-astronautics)
  • Palantir Technologies
  • The Trade Desk
Fully equipped laboratory facility designed for pharmaceutical or biotechnology research

Frequently Asked Questions

What is quantitative biosciences and engineering?

Quantitative biosciences and engineering (QBE) is an interdisciplinary field focused on using mathematics, computation, engineering and advanced quantitative methods to analyze and solve complex biological problems. This approach enables deeper understanding, prediction and manipulation of biological systems—from molecules to ecosystems—through data-driven, cross-disciplinary techniques.​

Quantitative biosciences and engineering merges training in biology with rigorous skills in mathematics, computational science, physics, chemistry and engineering. The aim is to prepare scientists and engineers who can tackle real-world biological questions using quantitative models, big data analysis and computational tools. Students gain hands-on research experience, often in collaboration with faculty from diverse scientific backgrounds and are prepared for innovation at the intersection of these disciplines.​

What are the most interesting advances and technologies in quantitative biosciences and engineering?

Recent advances shaping QBE include high-throughput DNA sequencing, single-cell genomics, computational modeling of biological networks, systems biology, synthetic biology, machine learning applied to biological data and genome editing technologies, like CRISPR. Modern QBE also leverages powerful statistical, data science and visualization tools to model complex biological systems, while advances in bioengineering are leading to new biomaterials, tissues and sustainable bioproducts.​

Career Options with a QBE Degree

Graduates with a degree in quantitative biosciences and engineering pursue diverse roles such as:

  • Bioinformatics or data scientist
  • Biostatistician
  • Biomedical or clinical engineer
  • Imaging scientist
  • Research scientist (in pharmaceuticals, agricultural biotech or environmental biosciences)
  • Quantitative biologist
  • Positions in medical, public health or clinical research
  • Many also pursue graduate or professional degrees in medicine, biomedical research or engineering.​
What Industries are hiring quantitative biosciences and engineering graduates?

Industries that commonly employ QBE graduates include:

  • Biotechnology and pharmaceuticals
  • Medical device and diagnostics companies
  • Healthcare and hospital systems
  • Environmental and sustainability sectors
  • Academic and government research labs
  • Data science or analytics firms with a health/life sciences focus
  • Food and agriculture technology, as well as startups focused on bio-based products.​
What are the current research directions in quantitative biosciences and engineering?

Current research in QBE is rapidly expanding into areas such as:

  • Synthetic and systems biology—designing novel genetic circuits and reprogramming cellular systems
  • Computational modeling of diseases, complex biological systems and epidemiology
  • Environmental biosciences, including bioremediation and bioenergy
  • Development of new diagnostic and therapeutic technologies (e.g., precision medicine, wearable biosensors)
  • Machine learning for big biological data, including image and omics data analysis
  • Modeling biological networks and evolutionary processes.​

This multidisciplinary field continues to evolve rapidly and offers exciting opportunities for research, innovation and impactful careers that bridge biology, engineering and computation.

Featured Alumni

Meet Hannah Miller ’23, MS ’24

As a senior data analyst at Eli Lilly and Company, Hannah Miller is passionate about leveraging data science to accelerate therapeutic research. Her time at Mines taught her how to approach complex problems from new perspectives and she felt deeply supported along the way. "It is such a special program, every single professor really wants you to succeed and I think that's really rare across engineering programs — you're not just a number to them, you're a person and they want you to do well and they care about you."