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Quantitative Biosciences and Engineering (Thesis)

Master of Science

Delivery Options

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Fall 2026 Deadline

Priority: December 15th
Domestic: July 1st
International: March 1st

Program Overview

The Quantitative Biosciences and Engineering master’s thesis program at Colorado School of Mines builds on your bachelor’s degree by combining biology, engineering and quantitative analysis to study complex biological systems. This program is designed for those who want to apply math-driven and data-informed approaches to biological questions with engineering relevance.

You will strengthen skills in modeling, data analysis, systems-level thinking and experimental design. Quantitative approaches are increasingly essential in biosciences where understanding complex interactions requires more than observation alone. This degree prepares you to analyze biological systems with rigor and translate findings into practical insight for research.

The thesis requirement allows you to conduct original interdisciplinary research, work closely with faculty and graduate with experience that reflects professional research environments. This program prepares you for technical roles at the intersection of biology and mathematical, computational and engineering sciences or for continued doctoral study.

Program Detail

This on-campus master’s thesis program combines interdisciplinary coursework with independent research. You will take graduate-level courses drawing from biosciences, engineering, applied mathematics and data analysis. Topics may include biological modeling, computational methods, quantitative analysis, experimental techniques and systems biology. Coursework is flexible and allows you to tailor your plan of study to align with your research interests and career goals.

The thesis is a key component of the degree. You will work with a faculty advisor to define a research question related to quantitative biosciences and engineering, conduct analytical, experimental or computational research and communicate your results through a written thesis and oral defense. Research often integrates data, modeling and biological experimentation.

Program Opportunities

Interdisciplinary research:

You collaborate across biology, engineering and quantitative disciplines at Mines.

Data and modeling focus:

Research emphasizes quantitative analysis, simulation and interpretation of biological systems.

Applied problem solving:

Projects connect biological understanding with engineering applications and system design.

Faculty Expertise

Meet three renowned faculty experts in computational biology, systems biology and synthetic biology who provide the rigorous quantitative expertise you need to solve complex challenges in the life sciences and biotechnology sectors.

John Spear profile picture

John Spear

Professor

Ramya Kumar profile picture

Ramya Kumar

Assistant Professor

Anne Silverman profile picture

Anne Silverman

Professor

Application Requirements

  • Bachelor's degree

  • GRE: Not Required

  • Letters of Recommendations (2 letters). Letters are not required for current Mines students.

  • Resume or Curriculum Vitae (CV)

  • Statement of Purpose

  • Transcripts

  • International students please review the English proficiency requirements

Program Curriculum

View Academic Catalog

World Class Labs, Centers and Facilities

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Functional Biomechanics Laboratory

The Functional Biomechanics Laboratory improves mobility in impaired and at-risk populations through targeted rehabilitation programs and device interventions. Led by Professor Anne Silverman, the lab investigates whole-body biomechanics with experimental and computational approaches, using motion capture, ground reaction force measurement and electromyography to quantify walking mechanics, coupled with detailed musculoskeletal models to generate movement simulations

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Diniz Behn Research Group

Professor Cecilia Diniz Behn applies multiscale mathematical modeling to investigate key research questions in metabolism, sleep and circadian rhythms. Her research group models key dynamics in whole-body metabolism including changes in glucose, glycerol, and insulin; sleep and circadian neurophysiology; and the diverse interactions among these systems.

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Krebs Research Group

Associate Professor Melissa Krebs develops biopolymer systems that allow the study of cells’ interactions with their microenvironment and that can be used for both tissue regeneration and therapeutics, with the end goal of improving patient therapies that are available in the clinic.

Salary Outlook

Median salary for recent program graduates $61,000. Learn more about Mines' comprehensive career development resources and this degree's salary potential.

Explore Mines Career Center

Employers who seek Mines graduates include

Biotechnology and life sciences

Companies such as

  • Genentech
  • Amgen
  • Pfizer
  • Merck
  • Thermo Fisher Scientific
Engineering and technology

Companies such as

  • Siemens
  • Abbott
  • Medtronic
  • GE Healthcare
  • Roche
Data and analytics

Companies such as

  • IBM
  • Google
  • Amazon
  • SAS
  • Palantir
Research and laboratories

Organizations such as

  • National Institutes of Health
  • National Laboratory of the Rockies
  • Los Alamos National Laboratory
  • Sandia National Laboratories
  • Broad Institute
Consulting and applied research

Companies such as

  • RTI International
  • Abt Associates
  • Booz Allen Hamilton
  • Deloitte
  • Accenture
Fully equipped laboratory facility designed for pharmaceutical or biotechnology research

Frequently Asked Questions

What is the value of a master’s degree in quantitative biosciences and engineering?

This degree provides advanced quantitative and interdisciplinary training that strengthens your ability to analyze biological systems and apply engineering methods in research and industry.

What advances are shaping this field right now?
  • Increased use of data-driven biological analysis
  • Integration of modeling with experimentation
  • Growth in systems-level biological research
  • Expanded application of quantitative methods in biosciences
What career opportunities will I have with this graduate degree?

Graduates pursue roles in bioengineering, quantitative analysis, research, systems biology or technical consulting. Many continue on to doctoral programs.

What industries hire individuals with this degree?

Industries include biotechnology, medical technology, engineering, data analytics, consulting and government research.

What types of research are common in this program?

Research areas often include biological modeling, data-intensive bioscience, systems analysis, experimental quantification and interdisciplinary applied studies.

Featured Alumni

Meet Hannah Miller ’23, MS ’24

As a senior data analyst at Eli Lilly and Company, Hannah Miller is passionate about leveraging data science to accelerate therapeutic research. Her time at Mines taught her how to approach complex problems from new perspectives and she felt deeply supported along the way. "It is such a special program, every single professor really wants you to succeed and I think that's really rare across engineering programs — you're not just a number to them, you're a person and they want you to do well and they care about you."